Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae

Sue E. Baum, Sharon A. Crawford, M. L. McElmeel, Cynthia G. Whitney, James H. Jorgensen

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The activity of AZD2563 against 250 highly resistant pneumococci and 267 drug-susceptible isolates was determined. The AZD2563 MICs for 50 and 90% of the strains tested were 1 and 2 μg/ml and 0.5 and 1 μg/ml, respectively, for the two isolate groups. These MICs were within 1 log2 dilution of those of linezolid.

Original languageEnglish (US)
Pages (from-to)3094-3095
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume46
Issue number9
DOIs
StatePublished - 2002

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Linezolid
Oxazolidinones
Streptococcus pneumoniae
Pharmaceutical Preparations
AZD2563

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae. / Baum, Sue E.; Crawford, Sharon A.; McElmeel, M. L.; Whitney, Cynthia G.; Jorgensen, James H.

In: Antimicrobial Agents and Chemotherapy, Vol. 46, No. 9, 2002, p. 3094-3095.

Research output: Contribution to journalArticle

Baum, Sue E. ; Crawford, Sharon A. ; McElmeel, M. L. ; Whitney, Cynthia G. ; Jorgensen, James H. / Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae. In: Antimicrobial Agents and Chemotherapy. 2002 ; Vol. 46, No. 9. pp. 3094-3095.
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