Community-associated Methicillin resistant Staphylococcus aureus pneumonia (CA-MRSA)

Marcela Mazo, John E. Stupka, Eric M. Mortensen, Antonio R Anzueto, Marcos Restrepo

Research output: Contribution to journalArticle

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) has been recognized as an in-hospital acquired pathogen responsible for an increasing number of cases of hospital and ventilator associated pneumonia. However, this previously considered a purely nosocomial pathogen has been diagnosed with increasing frequency at hospital admission and new infections and outbreaks have been reported in individuals from the community with absence of risk factors. This new strain of MRSA is currently recognized in the literature as community-associated MRSA (CA-MRSA). The spectrum of infections due to CA-MRSA can range from simple cutaneous abscesses and soft tissue infections to septic shock and severe necrotizing pneumonia. CA-MRSA pneumonia usually presents in a previously healthy individual with the presence of a previous influenza like illness followed by shortness of breath, bilateral pulmonary infiltrates, sepsis and prompt clinical detriment and death if no proper treatment is established soon. The objective of this review is to familiarize the clinician with CA-MRSA as cause of community acquired pneumonia, review the epidemiological, clinical, microbiological characteristics, in order to minimize delays in the administration of the adequate antimicrobial treatment to improve patient's outcomes of this deadly condition.

Original languageEnglish (US)
Pages (from-to)194-200
Number of pages7
JournalCurrent Respiratory Medicine Reviews
Volume6
Issue number3
DOIs
StatePublished - 2010

Fingerprint

Staphylococcal Pneumonia
Methicillin-Resistant Staphylococcus aureus
Pneumonia
Ventilator-Associated Pneumonia
Soft Tissue Infections
Septic Shock
Infection
Dyspnea
Abscess
Human Influenza
Disease Outbreaks
Sepsis
Lung
Skin
Therapeutics

Keywords

  • Antimicrobials
  • Diagnosis
  • Microbiology
  • MRSA
  • Pneumonia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Community-associated Methicillin resistant Staphylococcus aureus pneumonia (CA-MRSA). / Mazo, Marcela; Stupka, John E.; Mortensen, Eric M.; Anzueto, Antonio R; Restrepo, Marcos.

In: Current Respiratory Medicine Reviews, Vol. 6, No. 3, 2010, p. 194-200.

Research output: Contribution to journalArticle

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