Combination therapy in type 2 diabetes mellitus

Muhammad Abdul-Ghani; Ralph A. DeFronzo; Roy Eldor

doi:10.1002/9781118387658.ch46

Combination therapy in type 2 diabetes mellitus

Muhammad Abdul-Ghani, Ralph A. DeFronzo, Roy Eldor

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Type 2 diabetes mellitus (T2DM) is a complex metabolic and cardiovascular disorder with at least eight distinct pathophysiologic abnormalities. No one antidiabetic agent can reverse all eight of these pathogenic disturbances and successful treatment requires multiple agents used in combination. In the present chapter the use of combination therapy in two clinical situations is reviewed: (i) initiation of combination therapy in newly diagnosed T2DM patients, and (ii) add-on therapy in T2DM patients inadequately controlled with one or more oral agents.

Original language	English (US)
Title of host publication	International Textbook of Diabetes Mellitus
Publisher	wiley
Pages	686-708
Number of pages	23
ISBN (Electronic)	9781118387658
ISBN (Print)	9780470658611
DOIs	https://doi.org/10.1002/9781118387658.ch46
State	Published - Jan 1 2015

Keywords

combination therapy
type 2 diabetes

ASJC Scopus subject areas

General Medicine
General Social Sciences

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10.1002/9781118387658.ch46

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AB - Type 2 diabetes mellitus (T2DM) is a complex metabolic and cardiovascular disorder with at least eight distinct pathophysiologic abnormalities. No one antidiabetic agent can reverse all eight of these pathogenic disturbances and successful treatment requires multiple agents used in combination. In the present chapter the use of combination therapy in two clinical situations is reviewed: (i) initiation of combination therapy in newly diagnosed T2DM patients, and (ii) add-on therapy in T2DM patients inadequately controlled with one or more oral agents.

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ER -

Combination therapy in type 2 diabetes mellitus

Abstract

Keywords

ASJC Scopus subject areas

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