Abstract
Type 2 diabetes mellitus (T2DM) is a complex metabolic and cardiovascular disorder with at least eight distinct pathophysiologic abnormalities. No one antidiabetic agent can reverse all eight of these pathogenic disturbances and successful treatment requires multiple agents used in combination. In the present chapter the use of combination therapy in two clinical situations is reviewed: (i) initiation of combination therapy in newly diagnosed T2DM patients, and (ii) add-on therapy in T2DM patients inadequately controlled with one or more oral agents.
| Original language | English (US) |
|---|---|
| Title of host publication | International Textbook of Diabetes Mellitus |
| Publisher | wiley |
| Pages | 686-708 |
| Number of pages | 23 |
| ISBN (Electronic) | 9781118387658 |
| ISBN (Print) | 9780470658611 |
| DOIs | |
| State | Published - Jan 1 2015 |
Keywords
- combination therapy
- type 2 diabetes
ASJC Scopus subject areas
- General Medicine
- General Social Sciences
Fingerprint
Dive into the research topics of 'Combination therapy in type 2 diabetes mellitus'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS