Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis

Pukhraj Rishi, Anusha Venkataraman, Ekta Rishi

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

A 14-year-old girl presenting with visual loss in both eyes was diagnosed to have healed toxoplasma retinochoroiditis in the right eye with active choroidal neovascularization (CNV) secondary to toxoplasmosis in the left. She underwent combination photodynamic therapy (PDT) and intravitreal bevacizumab as primary treatment. PDT was performed as per the ′Treatment of Age-related Macular Degeneration by Photodynamic therapy′ study protocol and was followed by intravitreal bevacizumab after 2 days. CNV regressed at 8 weeks of follow-up and remained stable at 8 months of follow-up. The initial visual acuity improved from 20/120 to 20/30. Combination therapy with PDT and intravitreal bevacizumab appears to be effective in the treatment of CNV secondary to toxoplasma retinochoroiditis.

Original languageEnglish (US)
Pages (from-to)62-64
Number of pages3
JournalIndian Journal of Ophthalmology
Volume59
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

Keywords

  • Bevacizumab
  • choroidal neovascularization
  • photodynamic therapy
  • toxoplasmosis

ASJC Scopus subject areas

  • Ophthalmology

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