Abstract
Although macrophage colony-stimulating factor (CSF-1) has been suggested to play a role in maintaining the chronic inflammatory response in endometriosis, our data suggest that CSF-1 may also play a role in early endometriosis lesion formation. We have shown that CSF-1, in an autocrine fashion, has a direct effect on endometrial epithelial cell proliferation and attachment to peritoneal mesothelial cells, early steps in endometriosis lesion formation on the peritoneum.
Original language | English (US) |
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Pages (from-to) | 2464-2466 |
Number of pages | 3 |
Journal | Fertility and sterility |
Volume | 95 |
Issue number | 8 |
DOIs | |
State | Published - Jun 30 2011 |
Keywords
- Colony-stimulating factor 1
- c-fms
- early lesion development
- endometriosis
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology