Cognitive Processing Therapy for PTSD and Bipolar Disorder Comorbidity: A Case Study

John C Moring, Lauren M. Koch, Ashley Cherrington, Alan L. Peterson, Patricia A. Resick

Research output: Contribution to journalArticlepeer-review


There is a strong comorbidity between Posttraumatic Stress Disorder (PTSD) and bipolar disorder. Unfortunately, there is lack of dissemination regarding modifications of evidence-based therapies for PTSD among individuals with comorbid bipolar I disorder. Cognitive Processing Therapy (CPT) is one such evidence-based, gold-standard psychotherapy for PTSD that can be modified to address a wide-scope of symptoms either directly, or indirectly, related to traumatic events. This case study describes a female veteran with PTSD and comorbid bipolar I disorder who received CPT. Modifications of CPT were implemented during the later phase of therapy and were related to the management of hypomanic symptoms, medication adherence, and anxiety related to her self-trust and control regarding future manic episodes. The patient exhibited few symptoms of PTSD or depression at a 3-month follow-up and reported that CPT simultaneously helped her manage symptoms of bipolar disorder. A description the patient, necessary modifications, and strategies to address comorbid PTSD and bipolar I disorder are provided.

Original languageEnglish (US)
Pages (from-to)425-433
Number of pages9
JournalCognitive and Behavioral Practice
Issue number2
StatePublished - May 2022


  • PTSD
  • bipolar I disorder
  • case study
  • cognitive processing therapy
  • military
  • trauma

ASJC Scopus subject areas

  • Clinical Psychology


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