Coccidioidal Peritonitis: A Review of 17 Cases

Royce H. Johnson, Ritika Sharma, Rupam Sharma, Valerie Civelli, Vishal Narang, Rasha Kuran, Ellie J.C. Goldstein, Stan Deresinski, Amber Jones, Amin Ramzan, Irving Posalski, Dena El-Sayed, George R. Thompson, Carlos D'Assumpcao, Arash Heidari

Research output: Contribution to journalReview articlepeer-review


Coccidioidomycosis is the second most common endemic fungal infection in the United States. Prior descriptions of coccidioidal peritonitis include only single cases. We describe 17 new cases previously unreported from healthcare institutions in California. The majority of cases presented with nonspecific abdominal complaints. PubMed and Google Scholar were searched for additional case series and only single case reports and reviews of single cases were found. The diagnosis was confirmed by culture or histopathology and/or serology in each patient. All patients were treated with anti-fungal therapy. This case series demonstrates that coccidioidal peritonitis may be asymptomatic or present with only subtle abdominal symptoms. In a minority of our patients, the diagnosis was established incidentally during surgery. Based on this series, the overall outcome of coccidioidal peritonitis is favorable with long-Term triazole treatment. The term cure is not usually used in disseminated coccidioidal disease because of the risk of late relapse.

Original languageEnglish (US)
Article numberofac017
JournalOpen Forum Infectious Diseases
Issue number3
StatePublished - Mar 2022


  • coccidioidal peritonitis
  • peritoneal coccidioidomycosis and omental caking
  • peritonitis

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology


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