Coats' disease: An Indian perspective

Pukhraj Rishi, Ekta Rishi, Mahesh Uparkar, Tarun Sharma, Lingam Gopal, Pramod Bhende, Muna Bhende, Pratik Ranjan Sen, Parveen Sen

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Aim: To describe the clinical features, treatment and outcome patterns in 307 eyes with Coats' disease. Materials and Methods: Retrospective chart review of patients diagnosed with Coats' disease between January 1996 and January 2006 from a single referral center in southern India. Results: Two hundred and eighty patients (307 eyes) with mean age of 15.67 years (range: Four months-80 years) were included. Decreased vision (77%), unilateral affection (90%) and male preponderance (83.4%) were chief presenting features. Anterior segment involvement was seen in 67 (21.8%) eyes. Retinal telangiectasia were seen in 302 (99%) eyes, exudation in 274 (89%) eyes and retinal detachment in 158 (51.5%) eyes. Four-quadrant disease was seen in 207 (67.2 %) eyes. Visual acuity was < 20/200 in 249 (80.9%) eyes. One hundred and nine of 176 treated eyes (61.93%) had favorable anatomical outcome; 207 of 280 eyes (74%) had an optimal structural outcome. Seventeen (5.3%) eyes were enucleated. Complications following treatment included phthisis bulbi (7%), neovascular glaucoma (5%), epiretinal membrane (4.4%) and rubeosis iridis (4.4%). Conclusion: Indian patients with Coats' disease have a high male predominance, the majority of whom present with severe visual impairment and extensive four-quadrant exudation. Unusual presentations such as pain, vitreous hemorrhage and a high incidence of anterior segment involvement are distinctive to Indian eyes.

Original languageEnglish (US)
Pages (from-to)119-124
Number of pages6
JournalIndian Journal of Ophthalmology
Issue number2
StatePublished - Jun 1 2010
Externally publishedYes


  • Children
  • Coats' disease
  • Cryotherapy
  • Laser photocoagulation
  • Macular edema
  • Retinal detachment
  • Retinal telangiectasia

ASJC Scopus subject areas

  • Ophthalmology


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