Coagulation and fibrinolysis in pregnancies complicated by fetal growth retardation

M. G. Elder; L. Myatt

Coagulation and fibrinolysis in pregnancies complicated by fetal growth retardation

M. G. Elder, L. Myatt

Research output: Contribution to journal › Article › peer-review

Abstract

Saline extracts were made from portions of 17 normal placentae and from 8 placentae from pregnancies complicated by fetal growth retardation, but not hypertension. The ability of these extracts to inhibit urokinase-induced fibrinolysis was measured using a fibrin plate technique. Placental extracts from pregnancies complicated by fetal growth retardation exhibited greater inhibition of urokinase-induced fibrinolysis. There was no evidence of disseminated intravascular coagulation in these patients, but certain coagulation factors in the peripheral blood were raised.

Original language	English (US)
Pages (from-to)	355-360
Number of pages	6
Journal	British Journal of Obstetrics and Gynaecology
Volume	83
Issue number	5
State	Published - May 1976
Externally published	Yes

ASJC Scopus subject areas

Obstetrics and Gynecology

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title = "Coagulation and fibrinolysis in pregnancies complicated by fetal growth retardation",

abstract = "Saline extracts were made from portions of 17 normal placentae and from 8 placentae from pregnancies complicated by fetal growth retardation, but not hypertension. The ability of these extracts to inhibit urokinase-induced fibrinolysis was measured using a fibrin plate technique. Placental extracts from pregnancies complicated by fetal growth retardation exhibited greater inhibition of urokinase-induced fibrinolysis. There was no evidence of disseminated intravascular coagulation in these patients, but certain coagulation factors in the peripheral blood were raised.",

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AB - Saline extracts were made from portions of 17 normal placentae and from 8 placentae from pregnancies complicated by fetal growth retardation, but not hypertension. The ability of these extracts to inhibit urokinase-induced fibrinolysis was measured using a fibrin plate technique. Placental extracts from pregnancies complicated by fetal growth retardation exhibited greater inhibition of urokinase-induced fibrinolysis. There was no evidence of disseminated intravascular coagulation in these patients, but certain coagulation factors in the peripheral blood were raised.

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