Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells

  • Yannan Jia
  • , Lina Han
  • , Cassandra L. Ramage
  • , Zhe Wang
  • , Connie C. Weng
  • , Lei Yang
  • , Simona Colla
  • , Helen Ma
  • , Weiguo Zhang
  • , Michael Andreeff
  • , Naval Daver
  • , Nitin Jain
  • , Naveen Pemmaraju
  • , Kapil Bhalla
  • , Satu Mustjoki
  • , Peiyi Zhang
  • , Guangrong Zheng
  • , Daohong Zhou
  • , Qi Zhang
  • , Marina Konopleva

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

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Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science