Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

Thomas B. Shows; Alan Y. Sakaguchi; Susan L. Naylor; David V. Goeddel; Rihard M. Lawn

doi:10.1126/science.6181564

Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

Thomas B. Shows
, Alan Y. Sakaguchi
, Susan L. Naylor
, David V. Goeddel
, Rihard M. Lawn

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

At least ten leukocyte interferon genes and the single known fibroblast interferon gene have been localized on the pter→q12 region of human chromosome 9. Gene mapping was accomplished by blot hybridizations of cloned interferon complementary DNA to DNA from human-mouse cell hybrids with a translocation involving human chromosome 9. Supporting evidence suggests these genes are clustered.

Original language	English (US)
Pages (from-to)	373-374
Number of pages	2
Journal	Science
Volume	218
Issue number	4570
DOIs	https://doi.org/10.1126/science.6181564
State	Published - 1982
Externally published	Yes

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@article{aa036bca4cef4a3ea62a8840af066836,

title = "Clustering of leukocyte and fibroblast interferon genes on human chromosome 9",

abstract = "At least ten leukocyte interferon genes and the single known fibroblast interferon gene have been localized on the pter→q12 region of human chromosome 9. Gene mapping was accomplished by blot hybridizations of cloned interferon complementary DNA to DNA from human-mouse cell hybrids with a translocation involving human chromosome 9. Supporting evidence suggests these genes are clustered.",

author = "Shows, \{Thomas B.\} and Sakaguchi, \{Alan Y.\} and Naylor, \{Susan L.\} and Goeddel, \{David V.\} and Lawn, \{Rihard M.\}",

year = "1982",

doi = "10.1126/science.6181564",

language = "English (US)",

volume = "218",

pages = "373--374",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4570",

}

TY - JOUR

T1 - Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

AU - Shows, Thomas B.

AU - Sakaguchi, Alan Y.

AU - Naylor, Susan L.

AU - Goeddel, David V.

AU - Lawn, Rihard M.

PY - 1982

Y1 - 1982

N2 - At least ten leukocyte interferon genes and the single known fibroblast interferon gene have been localized on the pter→q12 region of human chromosome 9. Gene mapping was accomplished by blot hybridizations of cloned interferon complementary DNA to DNA from human-mouse cell hybrids with a translocation involving human chromosome 9. Supporting evidence suggests these genes are clustered.

AB - At least ten leukocyte interferon genes and the single known fibroblast interferon gene have been localized on the pter→q12 region of human chromosome 9. Gene mapping was accomplished by blot hybridizations of cloned interferon complementary DNA to DNA from human-mouse cell hybrids with a translocation involving human chromosome 9. Supporting evidence suggests these genes are clustered.

UR - https://www.scopus.com/pages/publications/0019948087

UR - https://www.scopus.com/pages/publications/0019948087#tab=citedBy

U2 - 10.1126/science.6181564

DO - 10.1126/science.6181564

M3 - Article

C2 - 6181564

AN - SCOPUS:0019948087

SN - 0036-8075

VL - 218

SP - 373

EP - 374

JO - Science

JF - Science

IS - 4570

ER -

Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

Abstract

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