Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

Thomas B. Shows, Alan Y. Sakaguchi, Susan L. Naylor, David V. Goeddel, Rihard M. Lawn

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

At least ten leukocyte interferon genes and the single known fibroblast interferon gene have been localized on the pter→q12 region of human chromosome 9. Gene mapping was accomplished by blot hybridizations of cloned interferon complementary DNA to DNA from human-mouse cell hybrids with a translocation involving human chromosome 9. Supporting evidence suggests these genes are clustered.

Original languageEnglish (US)
Pages (from-to)373-374
Number of pages2
JournalScience
Volume218
Issue number4570
DOIs
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • General

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