Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

Thomas B. Shows, Alan Y Sakaguchi, Susan L. Naylor, David V. Goeddel, Rihard M. Lawn

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

At least ten leukocyte interferon genes and the single known fibroblast interferon gene have been localized on the pter→q12 region of human chromosome 9. Gene mapping was accomplished by blot hybridizations of cloned interferon complementary DNA to DNA from human-mouse cell hybrids with a translocation involving human chromosome 9. Supporting evidence suggests these genes are clustered.

Original languageEnglish (US)
Pages (from-to)373-374
Number of pages2
JournalScience
Volume218
Issue number4570
StatePublished - 1982
Externally publishedYes

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Chromosomes, Human, Pair 9
Interferon-beta
Human Chromosomes
Interferon-alpha
Cluster Analysis
Genes
Hybrid Cells
Chromosome Mapping
Interferons
Complementary DNA
DNA

ASJC Scopus subject areas

  • General

Cite this

Shows, T. B., Sakaguchi, A. Y., Naylor, S. L., Goeddel, D. V., & Lawn, R. M. (1982). Clustering of leukocyte and fibroblast interferon genes on human chromosome 9. Science, 218(4570), 373-374.

Clustering of leukocyte and fibroblast interferon genes on human chromosome 9. / Shows, Thomas B.; Sakaguchi, Alan Y; Naylor, Susan L.; Goeddel, David V.; Lawn, Rihard M.

In: Science, Vol. 218, No. 4570, 1982, p. 373-374.

Research output: Contribution to journalArticle

Shows, TB, Sakaguchi, AY, Naylor, SL, Goeddel, DV & Lawn, RM 1982, 'Clustering of leukocyte and fibroblast interferon genes on human chromosome 9', Science, vol. 218, no. 4570, pp. 373-374.
Shows TB, Sakaguchi AY, Naylor SL, Goeddel DV, Lawn RM. Clustering of leukocyte and fibroblast interferon genes on human chromosome 9. Science. 1982;218(4570):373-374.
Shows, Thomas B. ; Sakaguchi, Alan Y ; Naylor, Susan L. ; Goeddel, David V. ; Lawn, Rihard M. / Clustering of leukocyte and fibroblast interferon genes on human chromosome 9. In: Science. 1982 ; Vol. 218, No. 4570. pp. 373-374.
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