Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell

Di Chen, Jian Q. Feng, Mei Feng, Marie A. Harris, Gregory R. Mundy, Stephen E. Harris

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

A cDNA clone encoding bone mophogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5′ noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalBBA - Gene Structure and Expression
Volume1174
Issue number3
DOIs
StatePublished - Sep 23 1993

Keywords

  • Bone morphogenetic protein 4
  • Nucleotide sequence
  • Tissue specificity
  • cDNA

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

Fingerprint Dive into the research topics of 'Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell'. Together they form a unique fingerprint.

Cite this