Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell

Di Chen, Jian Q. Feng, Mei Feng, Marie A. Harris, Gregory R. Mundy, Stephen E Harris

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A cDNA clone encoding bone mophogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5′ noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalBBA - Gene Structure and Expression
Volume1174
Issue number3
DOIs
StatePublished - Sep 23 1993

Fingerprint

Bone Morphogenetic Protein 4
Cloning
Rats
Organism Cloning
Complementary DNA
Bone
Clone Cells
Bone and Bones
Organ Specificity
Gene Library
Gene expression
Open Reading Frames
Prostate
Exons
Proteins
Tissue
Gene Expression
Amino Acids

Keywords

  • Bone morphogenetic protein 4
  • cDNA
  • Nucleotide sequence
  • Tissue specificity

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Genetics
  • Structural Biology

Cite this

Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell. / Chen, Di; Feng, Jian Q.; Feng, Mei; Harris, Marie A.; Mundy, Gregory R.; Harris, Stephen E.

In: BBA - Gene Structure and Expression, Vol. 1174, No. 3, 23.09.1993, p. 289-292.

Research output: Contribution to journalArticle

Chen, Di ; Feng, Jian Q. ; Feng, Mei ; Harris, Marie A. ; Mundy, Gregory R. ; Harris, Stephen E. / Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell. In: BBA - Gene Structure and Expression. 1993 ; Vol. 1174, No. 3. pp. 289-292.
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