Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell

Di Chen; Jian Q. Feng; Mei Feng; Marie A. Harris; Gregory R. Mundy; Stephen E Harris

doi:10.1016/0167-4781(93)90200-W

Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell

Di Chen, Jian Q. Feng, Mei Feng, Marie A. Harris, Gregory R. Mundy, Stephen E Harris

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A cDNA clone encoding bone mophogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5′ noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.

Original language	English (US)
Pages (from-to)	289-292
Number of pages	4
Journal	BBA - Gene Structure and Expression
Volume	1174
Issue number	3
DOIs	https://doi.org/10.1016/0167-4781(93)90200-W
State	Published - Sep 23 1993

Keywords

Bone morphogenetic protein 4
Nucleotide sequence
Tissue specificity
cDNA

ASJC Scopus subject areas

Structural Biology
Biophysics
Biochemistry
Genetics

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10.1016/0167-4781(93)90200-W

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abstract = "A cDNA clone encoding bone mophogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5′ noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.",

keywords = "Bone morphogenetic protein 4, Nucleotide sequence, Tissue specificity, cDNA",

author = "Di Chen and Feng, {Jian Q.} and Mei Feng and Harris, {Marie A.} and Mundy, {Gregory R.} and Harris, {Stephen E}",

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T1 - Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell

AU - Chen, Di

AU - Feng, Jian Q.

AU - Feng, Mei

AU - Harris, Marie A.

AU - Mundy, Gregory R.

AU - Harris, Stephen E

PY - 1993/9/23

Y1 - 1993/9/23

N2 - A cDNA clone encoding bone mophogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5′ noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.

AB - A cDNA clone encoding bone mophogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5′ noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.

KW - Bone morphogenetic protein 4

KW - Nucleotide sequence

KW - Tissue specificity

KW - cDNA

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JO - Biochimica et Biophysica Acta - Gene Structure and Expression

JF - Biochimica et Biophysica Acta - Gene Structure and Expression

IS - 3

ER -

Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell

Abstract

Keywords

ASJC Scopus subject areas

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