Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais

Aline Mansueto Mourão, Luiz Sérgio Mageste Barbosa, Elizabeth Regina Comini-Frota, Denise Da Silva Freitas, Rodrigo Santiago Gomez, Ted M. Burns, Stela Maris Aguiar Lemos, Antonio Lúcio Teixeira

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature.

Original languageEnglish (US)
Pages (from-to)156-160
Number of pages5
JournalRevista da Associacao Medica Brasileira
Volume61
Issue number2
DOIs
StatePublished - Mar 1 2015
Externally publishedYes

Keywords

  • Epidemiology
  • Myasthenia gravis
  • Neurology
  • Therapeutics
  • Thymectomy

ASJC Scopus subject areas

  • General Medicine

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