TY - JOUR
T1 - Clinical evaluation of an immbolization system for stereotactic body radiotherapy using helical tomotherapy
AU - Gutiérrez, Alonso N.
AU - Stathakis, Sotirios
AU - Crownover, Richard
AU - Esquivel, Carlos
AU - Shi, Chengyu
AU - Papanikolaou, Niko
PY - 2011
Y1 - 2011
N2 - In this study, a clinical evaluation of the Body Pro-Lok™ System combined with the TomoTherapy megavoltage computed tomography (MVCT) was performed for lung and liver stereotactic body radiotherapy (SBRT) to reduce interfractional setup uncertainty. Twenty patients treated with 3-5 fractions of SBRT were analyzed retrospectively. The Body Pro-Lok™ system was used in both CT simulation and during patient treatment setup. Patients were immobilized with a vacuum cushion placed posteriorly over the thoracic region, an abdominal compression plate, and a knee and foot sponge. Pretreatment MVCT scans of the TomoTherapy HI-ART II unit were fused with the planning kVCT before delivery of each fraction to determine the interfractional setup error. A total of 84 shifts were analyzed to assess the interfractional setup accuracy. Results showed that the mean interfractional setup errors and standard deviations were -0.9 ± 3.1 mm, 1.2 ± 5.5 mm, and 6.5 ± 2.6 mm for lateral (IEC-X), longitudinal (IEC-Y), and vertical (IEC-Z) variations, respectively. The maximum motion was 17.1 mm in the longitudinal direction. When all 3 translational coordinates were analyzed, a mean composite displacement vector of 8.2 ± 2.0 mm (range 4.1-11.7 mm) was obtained for all patients. Based on the findings, image-guided SBRT using the Body Pro-Lok™ system in conjunction with the MVCT of TomoTherapy is capable of minimizing interfractional setup error and improving treatment accuracy.
AB - In this study, a clinical evaluation of the Body Pro-Lok™ System combined with the TomoTherapy megavoltage computed tomography (MVCT) was performed for lung and liver stereotactic body radiotherapy (SBRT) to reduce interfractional setup uncertainty. Twenty patients treated with 3-5 fractions of SBRT were analyzed retrospectively. The Body Pro-Lok™ system was used in both CT simulation and during patient treatment setup. Patients were immobilized with a vacuum cushion placed posteriorly over the thoracic region, an abdominal compression plate, and a knee and foot sponge. Pretreatment MVCT scans of the TomoTherapy HI-ART II unit were fused with the planning kVCT before delivery of each fraction to determine the interfractional setup error. A total of 84 shifts were analyzed to assess the interfractional setup accuracy. Results showed that the mean interfractional setup errors and standard deviations were -0.9 ± 3.1 mm, 1.2 ± 5.5 mm, and 6.5 ± 2.6 mm for lateral (IEC-X), longitudinal (IEC-Y), and vertical (IEC-Z) variations, respectively. The maximum motion was 17.1 mm in the longitudinal direction. When all 3 translational coordinates were analyzed, a mean composite displacement vector of 8.2 ± 2.0 mm (range 4.1-11.7 mm) was obtained for all patients. Based on the findings, image-guided SBRT using the Body Pro-Lok™ system in conjunction with the MVCT of TomoTherapy is capable of minimizing interfractional setup error and improving treatment accuracy.
KW - Immobilization
KW - Stereotactic radiotherapy
KW - Tomotherapy
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U2 - 10.1016/j.meddos.2010.02.003
DO - 10.1016/j.meddos.2010.02.003
M3 - Article
C2 - 20435464
AN - SCOPUS:79955470415
SN - 0958-3947
VL - 36
SP - 126
EP - 129
JO - Medical Dosimetry
JF - Medical Dosimetry
IS - 2
ER -