Clinical evaluation of an immbolization system for stereotactic body radiotherapy using helical tomotherapy

Alonso N. Gutiérrez, Sotirios Stathakis, Richard Crownover, Carlos Esquivel, Chengyu Shi, Niko Papanikolaou

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

In this study, a clinical evaluation of the Body Pro-Lok System combined with the TomoTherapy megavoltage computed tomography (MVCT) was performed for lung and liver stereotactic body radiotherapy (SBRT) to reduce interfractional setup uncertainty. Twenty patients treated with 3-5 fractions of SBRT were analyzed retrospectively. The Body Pro-Lok system was used in both CT simulation and during patient treatment setup. Patients were immobilized with a vacuum cushion placed posteriorly over the thoracic region, an abdominal compression plate, and a knee and foot sponge. Pretreatment MVCT scans of the TomoTherapy HI-ART II unit were fused with the planning kVCT before delivery of each fraction to determine the interfractional setup error. A total of 84 shifts were analyzed to assess the interfractional setup accuracy. Results showed that the mean interfractional setup errors and standard deviations were -0.9 ± 3.1 mm, 1.2 ± 5.5 mm, and 6.5 ± 2.6 mm for lateral (IEC-X), longitudinal (IEC-Y), and vertical (IEC-Z) variations, respectively. The maximum motion was 17.1 mm in the longitudinal direction. When all 3 translational coordinates were analyzed, a mean composite displacement vector of 8.2 ± 2.0 mm (range 4.1-11.7 mm) was obtained for all patients. Based on the findings, image-guided SBRT using the Body Pro-Lok system in conjunction with the MVCT of TomoTherapy is capable of minimizing interfractional setup error and improving treatment accuracy.

Original languageEnglish (US)
Pages (from-to)126-129
Number of pages4
JournalMedical Dosimetry
Volume36
Issue number2
DOIs
StatePublished - Jan 1 2011

Keywords

  • Immobilization
  • Stereotactic radiotherapy
  • Tomotherapy

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Oncology
  • Radiology Nuclear Medicine and imaging

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