Circulating iga immune complexes in aids

Marilyn M. Lightfoote, Thomas M. Folks, Robert Redfield, Jonathan Gold, Kenneth W. Sell

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Circulating immune complexes were isolated from the serum of patients with AIDS, as well as patients with other acute and chronic viral diseases. Analysis of these immune complexes by methods of flow cytometry and by radioimmune (Raji cell) assay revealed a prevalence of IgA complexes in the serum of AIDS patients and a prevalence of IgG complexes in the serum of patients with other viral diseases. Raji cells bind immune complexes via Fc and complement (C,) receptors and may detect IgA immune complexes more efficiently than a Clq assay since IgA has no affinity for Clq.

Original languageEnglish (US)
Pages (from-to)341-345
Number of pages5
JournalImmunological Investigations
Volume14
Issue number4
DOIs
StatePublished - 1985
Externally publishedYes

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Antigen-Antibody Complex
Immunoglobulin A
Virus Diseases
Acquired Immunodeficiency Syndrome
Serum
Complement Receptors
Flow Cytometry
Chronic Disease
Immunoglobulin G

ASJC Scopus subject areas

  • Immunology

Cite this

Lightfoote, M. M., Folks, T. M., Redfield, R., Gold, J., & Sell, K. W. (1985). Circulating iga immune complexes in aids. Immunological Investigations, 14(4), 341-345. https://doi.org/10.3109/08820138509022669

Circulating iga immune complexes in aids. / Lightfoote, Marilyn M.; Folks, Thomas M.; Redfield, Robert; Gold, Jonathan; Sell, Kenneth W.

In: Immunological Investigations, Vol. 14, No. 4, 1985, p. 341-345.

Research output: Contribution to journalArticle

Lightfoote, MM, Folks, TM, Redfield, R, Gold, J & Sell, KW 1985, 'Circulating iga immune complexes in aids', Immunological Investigations, vol. 14, no. 4, pp. 341-345. https://doi.org/10.3109/08820138509022669
Lightfoote MM, Folks TM, Redfield R, Gold J, Sell KW. Circulating iga immune complexes in aids. Immunological Investigations. 1985;14(4):341-345. https://doi.org/10.3109/08820138509022669
Lightfoote, Marilyn M. ; Folks, Thomas M. ; Redfield, Robert ; Gold, Jonathan ; Sell, Kenneth W. / Circulating iga immune complexes in aids. In: Immunological Investigations. 1985 ; Vol. 14, No. 4. pp. 341-345.
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