Abstract
The presence of deiodinase activity in the mammalian pineal was noted 2 years ago. Since then, a marked rhythm in the activity has been described with the nighttime increase being mediated by the release of NE from sympathetic nerve ending which subsequently acts primarily on β-adrenergic receptors with cAMP serving as the intracellular second messenger. The functional significance of this marked 24 hour rhythm remains unknown.
Original language | English (US) |
---|---|
Pages (from-to) | 95-98 |
Number of pages | 4 |
Journal | Annual Review of Chronopharmacology |
Volume | 5 |
State | Published - Jan 1 1988 |
ASJC Scopus subject areas
- Pharmacology