Cigarette Smoke, DNA Damage Repair, and Human Health

A. S. Jaiswal, S. K. Connors, M. L. Armas, H. Panda, S. Narayan, C. G. Gairola

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Cigarette smoking is associated with numerous adverse health effects caused to nearly every organ of the body, which account for an estimated 438 000 deaths, or nearly one of every five deaths each year in the United States (Centers for disease Control and Prevention, Department of Health and Human Services, Fact Sheet, January 2008). Cigarette smoking is linked with coronary heart disease and different types of cancers, including lung, bladder, esophagus, kidney, pancreas, cervical, colon, and breast. Other than epidemiological studies, more scientific facts are emerging to establish more firmly the causal relationship of cigarette smoking with different types of cancers.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Environmental Health
PublisherElsevier Inc.
Pages669-679
Number of pages11
ISBN (Print)9780444522726
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

Keywords

  • Adenomatous polyposis coli (APC)
  • Carcinogenesis
  • Cigarette smoke carcinogens
  • DNA damage
  • DNA repair
  • Metabolic detoxification
  • Mutagenesis

ASJC Scopus subject areas

  • Environmental Science(all)

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