Chylothorax in Henoch-Schonlein purpura: A case report and review of the literature

Bryan D. Cogar, Ted D. Groshong, Brian K. Turpin, Jesus R. Guajardo

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Henoch-Schonlein purpura (HSP) is the most common acute vasculitis in the pediatric population, with an incidence of 10-14 per 100,000. The classic presentation of this disorder includes erythematous papules followed by palpable purpura in the lower extremities, trunk, and face, arthralgia or arthritis, abdominal pain, gastrointestinal bleeding, and nephritis. While renal abnormalities in HSP are common, the classic pulmonary manifestations, such as hemorrhage and pneumonitis, are thought to be infrequent. Subclinical pulmonary manifestations, including diffusion defects and radiographic anomalies, seem to be quite frequent in patients with HSP but are not commonly reported. Other respiratory manifestations include pleural effusion and chylothorax, but these are rarely mentioned in the literature. Chylothorax was only reported once in an adult patient with HSP in whom the mechanism of formation was demonstrated to be secondary to transdiaphragmatic passage of chylous fluid from the peritoneal cavity. Here we describe an 8-year-old girl with HSP, nephrotic syndrome, and chylothorax, and we report the results of a review of the literature regarding respiratory complications in HSR The present case is the first pediatric patient reported with HSP and chylothorax. The therapeutic measures utilized were effective in resolving her edema, ascites, and chylothorax, and we advocate the use of these measures as first-line therapy in future patients with similar complications from HSP.

Original languageEnglish (US)
Pages (from-to)563-567
Number of pages5
JournalPediatric Pulmonology
Issue number6
StatePublished - Jun 2005
Externally publishedYes


  • Chylothorax
  • Henoch-Schonlein purpura
  • Nephrotic syndrome
  • Pleural effusion
  • Pulmonary-renal syndrome
  • Vasculitis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Pediatrics, Perinatology, and Child Health


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