Chromosome localization of the human renin gene (REN) by in situ hybridization

J. R. McGill, J. M. Chirgwin, C. M. Moore, J. L. McCombs

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Previous studies by Southern blot analysis of human x mouse somatic cell hybrids localized the renin gene to region p21→qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25→q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.

Original languageEnglish (US)
Pages (from-to)55-57
Number of pages3
JournalCytogenetics and Cell Genetics
Issue number1
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Cell Biology


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