Chromosome localization of the human renin gene (REN) by in situ hybridization

J. R. McGill; J. M. Chirgwin; C. M. Moore; J. L. McCombs

doi:10.1159/000132425

Chromosome localization of the human renin gene (REN) by in situ hybridization

J. R. McGill, J. M. Chirgwin, C. M. Moore, J. L. McCombs

Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Previous studies by Southern blot analysis of human x mouse somatic cell hybrids localized the renin gene to region p21→qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25→q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.

Original language	English (US)
Pages (from-to)	55-57
Number of pages	3
Journal	Cytogenetics and Cell Genetics
Volume	45
Issue number	1
DOIs	https://doi.org/10.1159/000132425
State	Published - 1987

ASJC Scopus subject areas

Genetics
Cell Biology

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title = "Chromosome localization of the human renin gene (REN) by in situ hybridization",

abstract = "Previous studies by Southern blot analysis of human x mouse somatic cell hybrids localized the renin gene to region p21→qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25→q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.",

author = "McGill, {J. R.} and Chirgwin, {J. M.} and Moore, {C. M.} and McCombs, {J. L.}",

year = "1987",

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AU - McCombs, J. L.

PY - 1987

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AB - Previous studies by Southern blot analysis of human x mouse somatic cell hybrids localized the renin gene to region p21→qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25→q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.

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