Abstract
Lactotransferrin (LTF) is an important member of the transferrin family of proteins. These proteins play an essential role in the transport of iron in extracellular fluid (Aisen and Listowsky, 1980). Southern blot analysis of mouse-human somatic cell hybrids have localized the LTF gene to region q1→qter of human chromosome 3 (Teng et al., unpublished data). Using the same full-length mouse cDNA probe (2.2 kb), the LTF gene was mapped to human chromosomal bands 3q21→q23 by in situ hybridization. The sublocalization of the LTF gene to 3q21→q23 is in the region of human chromosome 3 where the gene loci of transferrin and transferrin receptor have been localized. (Yang et al., 1984; van de Rijn et al., 1983).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16-17 |
| Number of pages | 2 |
| Journal | Cytogenetics and Cell Genetics |
| Volume | 47 |
| Issue number | 1-2 |
| State | Published - 1988 |
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ASJC Scopus subject areas
- Cell Biology
- Genetics
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Chromosomal localization of human lactotransferrin gene (LTF) by in situ hybridization. / McCombs, J. L.; Teng, C. T.; Pentecost, B. T.; Magnuson, V. L.; Moore, C. M.; McGill, J. R.
In: Cytogenetics and Cell Genetics, Vol. 47, No. 1-2, 1988, p. 16-17.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Chromosomal localization of human lactotransferrin gene (LTF) by in situ hybridization
AU - McCombs, J. L.
AU - Teng, C. T.
AU - Pentecost, B. T.
AU - Magnuson, V. L.
AU - Moore, C. M.
AU - McGill, J. R.
PY - 1988
Y1 - 1988
N2 - Lactotransferrin (LTF) is an important member of the transferrin family of proteins. These proteins play an essential role in the transport of iron in extracellular fluid (Aisen and Listowsky, 1980). Southern blot analysis of mouse-human somatic cell hybrids have localized the LTF gene to region q1→qter of human chromosome 3 (Teng et al., unpublished data). Using the same full-length mouse cDNA probe (2.2 kb), the LTF gene was mapped to human chromosomal bands 3q21→q23 by in situ hybridization. The sublocalization of the LTF gene to 3q21→q23 is in the region of human chromosome 3 where the gene loci of transferrin and transferrin receptor have been localized. (Yang et al., 1984; van de Rijn et al., 1983).
AB - Lactotransferrin (LTF) is an important member of the transferrin family of proteins. These proteins play an essential role in the transport of iron in extracellular fluid (Aisen and Listowsky, 1980). Southern blot analysis of mouse-human somatic cell hybrids have localized the LTF gene to region q1→qter of human chromosome 3 (Teng et al., unpublished data). Using the same full-length mouse cDNA probe (2.2 kb), the LTF gene was mapped to human chromosomal bands 3q21→q23 by in situ hybridization. The sublocalization of the LTF gene to 3q21→q23 is in the region of human chromosome 3 where the gene loci of transferrin and transferrin receptor have been localized. (Yang et al., 1984; van de Rijn et al., 1983).
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UR - http://www.scopus.com/inward/citedby.url?scp=0023922603&partnerID=8YFLogxK
M3 - Article
C2 - 3356163
AN - SCOPUS:0023922603
VL - 47
SP - 16
EP - 17
JO - Cytogenetic and Genome Research
JF - Cytogenetic and Genome Research
SN - 1424-8581
IS - 1-2
ER -