Abstract
Lactotransferrin (LTF) is an important member of the transferrin family of proteins. These proteins play an essential role in the transport of iron in extracellular fluid (Aisen and Lis-towsky. 1980). Southern blot analysis of mouse-human somatic cell hybrids have localized the LTF gene to region q21→qter of human chromosome 3 (Teng et al., unpublished data). Using the same full-length mouse cDNA probe (2.2 kb), the LTF gene was mapped to human chromosomal bands 3q21→q23 by in situ hybridization. The sublocalization of the LTF gene to 3q21→q23 is in the region of human chromosome 3 where the gene loci of transferrin and transferrin receptor have been localized (Yang et al. 1984; van dc Rijn el al. 1983).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16-17 |
| Number of pages | 2 |
| Journal | Cytogenetic and Genome Research |
| Volume | 47 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 1 1988 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Genetics(clinical)
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McCombs, J. L., Teng, C. T., Pentecost, B. T., Magnuson, V. L., Moore, C. M., & McGill, J. R. (1988). Chromosomal localization of human lactotransferrin gene (Ltf) by in situ hybridization. Cytogenetic and Genome Research, 47(1-2), 16-17. https://doi.org/10.1159/000132496