Chromosomal localization of group-specific component by in situ hybridization

J. L. McCombs, F. Yang, B. H. Bowman, J. R. McGill, Charleen M Moore

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Group-specific component (GC), an alpha2-globulin plasma protein synthesized primarily in the liver, is the major vitamin D-binding protein in plasma. It has two common phenotypes, GC1 and GC2, which appears in all human populations. Using the cDNA insert containing the entire coding sequence of GC2, the GC gene was mapped to human chromosomal bands 4q13→q21.1 by in situ hybridization.

Original languageEnglish (US)
Pages (from-to)62-64
Number of pages3
JournalCytogenetics and Cell Genetics
Issue number1-2
StatePublished - 1986

ASJC Scopus subject areas

  • Genetics
  • Cell Biology


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