Chromosomal assignments of human 27-kDa heat shock protein gene family

Sean E. McGuire, Suzanne A.W. Fuqua, Susan L. Naylor, Denise A. Helin-Davis, William L. McGuire

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

The 27-kDa human heat shock protein (hsp27) is dually regulated by both estrogen and heat shock treatment. Its function is obscure, but the high degree of homology to the lens α-crystallins and to the small heat shock proteins of Drosophila suggests that it may serve a structural function. There are at least three related human hsp27 sequences. To provide possible insight into the dual regulation of hsp27, we have determined the chromosomal location of all these and found them to be on separate chromosomes: 3, 9, and X.

Original languageEnglish (US)
Pages (from-to)167-171
Number of pages5
JournalSomatic Cell and Molecular Genetics
Volume15
Issue number2
DOIs
StatePublished - Mar 1989

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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