Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death

Hui Jiang, Xiaoyu Xue, Swarupa Panda, Ajinkya Kawale, Richard M. Hooy, Fengshan Liang, Jungsan Sohn, Patrick Sung, Nelson O. Gekara

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192 Scopus citations

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Biochemistry, Genetics and Molecular Biology