Optimum conditions for the hydrolyses of the conjugated metabolites of chlorpromazine have been developed. Enzymatic procedure under such conditions yields 80 per cent hydrolysis in 1 hour. The rates of hydrolyses of individual metabolite conjugates have been determined. The time required for maximum hydrolysis of all the known conjugates varies between 1 and 4 hours.
|Original language||English (US)|
|Number of pages||9|
|Journal||The Journal of Laboratory and Clinical Medicine|
|State||Published - Mar 1973|
ASJC Scopus subject areas
- Pathology and Forensic Medicine