Chemotherapeutic induction of labour. A rational approach

Elly M.J. Xenakis, Jeanna M. Piper

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Induction of labour, defined as stimulation of uterine contractions before the spontaneous onset of labour, is indicated when the condition of the mother or fetus precludes awaiting the onset of spontaneous labour. In current medical practice, induction of labour comprises 2 phases: cervical priming and induction of contractions. Although numerous agents have been used for cervical priming, the current standard of care is the use of intracervical or intravaginal prostaglandin E2. The only drug currently used for induction of contractions is intravenous oxytocin. While many protocols are deemed acceptable, when required, the use of cervical priming, amniotomy and intravenous oxytocin are advocated. Utilising this approach, rapid delivery can be obtained in the majority of women.

Original languageEnglish (US)
Pages (from-to)61-68
Number of pages8
JournalDrugs
Volume54
Issue number1
DOIs
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Pharmacology (medical)

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