TY - JOUR
T1 - Chemoprevention of prostate cancer
T2 - Focus on key opportunities and clinical trials
AU - Leach, Robin
AU - Pollock, Brad
AU - Basler, Joseph
AU - Troyer, Dean
AU - Naylor, Susan
AU - Thompson, Ian M
PY - 2003/5
Y1 - 2003/5
N2 - By 2004-2005, the final results of the Prostate Cancer Prevention Trial should be available. Within several years thereafter, results of the SELECT should be available. The growing list of potential agents for prostate cancer prevention continues to grow and includes COX-2 inhibitors, vitamin D, dietary interventions (soy, isoflavenoids, low-fat diet), and many others. As prospective trials are completed and molecular genetic correlations are developed, it is almost certain that specific recommendations, tailored to the individual patient, will be developed. Ultimately, through these efforts, it can be anticipated that the primary focus for control of prostate cancer will shift from early detection and treatment to prevention.
AB - By 2004-2005, the final results of the Prostate Cancer Prevention Trial should be available. Within several years thereafter, results of the SELECT should be available. The growing list of potential agents for prostate cancer prevention continues to grow and includes COX-2 inhibitors, vitamin D, dietary interventions (soy, isoflavenoids, low-fat diet), and many others. As prospective trials are completed and molecular genetic correlations are developed, it is almost certain that specific recommendations, tailored to the individual patient, will be developed. Ultimately, through these efforts, it can be anticipated that the primary focus for control of prostate cancer will shift from early detection and treatment to prevention.
UR - http://www.scopus.com/inward/record.url?scp=0242584815&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0242584815&partnerID=8YFLogxK
U2 - 10.1016/S0094-0143(02)00178-7
DO - 10.1016/S0094-0143(02)00178-7
M3 - Review article
C2 - 12735500
AN - SCOPUS:0242584815
SN - 0094-0143
VL - 30
SP - 227
EP - 237
JO - Urologic Clinics of North America
JF - Urologic Clinics of North America
IS - 2
ER -