TY - JOUR
T1 - Chemoprevention of Prostate Cancer
AU - Brand, Timothy C.
AU - Canby-Hagino, Edith D.
AU - Pratap Kumar, A.
AU - Ghosh, Rita
AU - Leach, Robin J.
AU - Thompson, Ian M.
PY - 2006/8
Y1 - 2006/8
N2 - Prostate cancer is a common malignancy with multiple potential opportunities for cancer prevention. As the genetic basis of this malignancy is further understood, prevention strategies will be developed for individual patients based on specific risk factors and pathways of carcinogenesis. The PCPT has conclusively proven that prostate cancer prevention is possible. The results of the SELECT should be available within several years. An enormous challenge for the medical community will be the development of an efficient strategy to evaluate the substantial number of dietary, behavioral, and pharmacologic prevention opportunities. Ultimately, the goal of prostate cancer prevention is to (1) identify men who are destined to develop clinically significant prostate cancer, and (2) provide individualized agents to prevent disease development.
AB - Prostate cancer is a common malignancy with multiple potential opportunities for cancer prevention. As the genetic basis of this malignancy is further understood, prevention strategies will be developed for individual patients based on specific risk factors and pathways of carcinogenesis. The PCPT has conclusively proven that prostate cancer prevention is possible. The results of the SELECT should be available within several years. An enormous challenge for the medical community will be the development of an efficient strategy to evaluate the substantial number of dietary, behavioral, and pharmacologic prevention opportunities. Ultimately, the goal of prostate cancer prevention is to (1) identify men who are destined to develop clinically significant prostate cancer, and (2) provide individualized agents to prevent disease development.
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U2 - 10.1016/j.hoc.2006.03.012
DO - 10.1016/j.hoc.2006.03.012
M3 - Review article
C2 - 16861117
AN - SCOPUS:33746029437
SN - 0889-8588
VL - 20
SP - 831
EP - 843
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 4
ER -