Chemokines as potential markers in pediatric renal diseases

Ana Cristina Simões E Silva; André Barreto Pereira; Mauro Martins Teixeira; Antônio Lúcio Teixeira

doi:10.1155/2014/278715

Chemokines as potential markers in pediatric renal diseases

Ana Cristina Simões E Silva, André Barreto Pereira, Mauro Martins Teixeira, Antônio Lúcio Teixeira

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Glomerular diseases and obstructive uropathies are the two most frequent causes of chronic kidney disease (CKD) in children. Recently, biomarkers have become a focus of clinical research as potentially useful diagnostic tools in pediatric renal diseases. Among several putative biomarkers, chemokines emerge as promising molecules since they play relevant roles in the pathophysiology of pediatric renal diseases. The evaluation of these inflammatory mediators might help in the management of diverse renal diseases in children and the detection of patients at high risk to develop CKD. The aim of this paper is to revise general aspects of chemokines and the potential link between chemokines and the most common pediatric renal diseases by including experimental and clinical evidence.

Original language	English (US)
Article number	278715
Journal	Disease Markers
Volume	2014
DOIs	https://doi.org/10.1155/2014/278715
State	Published - 2014
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics
Clinical Biochemistry
Biochemistry, medical

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title = "Chemokines as potential markers in pediatric renal diseases",

abstract = "Glomerular diseases and obstructive uropathies are the two most frequent causes of chronic kidney disease (CKD) in children. Recently, biomarkers have become a focus of clinical research as potentially useful diagnostic tools in pediatric renal diseases. Among several putative biomarkers, chemokines emerge as promising molecules since they play relevant roles in the pathophysiology of pediatric renal diseases. The evaluation of these inflammatory mediators might help in the management of diverse renal diseases in children and the detection of patients at high risk to develop CKD. The aim of this paper is to revise general aspects of chemokines and the potential link between chemokines and the most common pediatric renal diseases by including experimental and clinical evidence.",

author = "{Sim{\~o}es E Silva}, {Ana Cristina} and Pereira, {Andr{\'e} Barreto} and Teixeira, {Mauro Martins} and Teixeira, {Ant{\^o}nio L{\'u}cio}",

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T1 - Chemokines as potential markers in pediatric renal diseases

AU - Simões E Silva, Ana Cristina

AU - Pereira, André Barreto

AU - Teixeira, Mauro Martins

AU - Teixeira, Antônio Lúcio

PY - 2014

Y1 - 2014

N2 - Glomerular diseases and obstructive uropathies are the two most frequent causes of chronic kidney disease (CKD) in children. Recently, biomarkers have become a focus of clinical research as potentially useful diagnostic tools in pediatric renal diseases. Among several putative biomarkers, chemokines emerge as promising molecules since they play relevant roles in the pathophysiology of pediatric renal diseases. The evaluation of these inflammatory mediators might help in the management of diverse renal diseases in children and the detection of patients at high risk to develop CKD. The aim of this paper is to revise general aspects of chemokines and the potential link between chemokines and the most common pediatric renal diseases by including experimental and clinical evidence.

AB - Glomerular diseases and obstructive uropathies are the two most frequent causes of chronic kidney disease (CKD) in children. Recently, biomarkers have become a focus of clinical research as potentially useful diagnostic tools in pediatric renal diseases. Among several putative biomarkers, chemokines emerge as promising molecules since they play relevant roles in the pathophysiology of pediatric renal diseases. The evaluation of these inflammatory mediators might help in the management of diverse renal diseases in children and the detection of patients at high risk to develop CKD. The aim of this paper is to revise general aspects of chemokines and the potential link between chemokines and the most common pediatric renal diseases by including experimental and clinical evidence.

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DO - 10.1155/2014/278715

M3 - Review article

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SN - 0278-0240

VL - 2014

JO - Disease Markers

JF - Disease Markers

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ER -

Chemokines as potential markers in pediatric renal diseases

Abstract

ASJC Scopus subject areas

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