Abstract
Column chromatographic fractionation of the methanol and ethyl acetate extracts of the stem-bark of Anacardium occidentale led to the isolation of five compounds (1-5). Their structures were determined by spectroscopic means by comparing spectral data to be β-sitosterol (1), 2,4-dihydroxy acetophenone (2), 1-monolinolein (3), ethyl oleate (4) and β-sitosterol-3-O-β-D-glucopyranoside (5). These compounds were evaluated for cytotoxicity against human cancer cell lines: A549, SCOV3 and rat normal cell line NRK49f. Compounds 2-5 were for the first time isolated from A. occidentale.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 62-67 |
| Number of pages | 6 |
| Journal | Natural Product Sciences |
| Volume | 28 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2022 |
| Externally published | Yes |
Keywords
- Anacardiaceae
- Anacardium occidentale
- MTT assay
- cytotoxicity
- β-sitosterol
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry
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