Characterization of the age-dependent shape of the pediatric thoracic spine and vertebrae using generalized procrustes analysis

James R. Peters, Robert M. Campbell, Sriram Balasubramanian

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Generalized Procrustes Analysis (GPA) is a superimposition method used to generate size-invariant distributions of homologous landmark points. Several studies have used GPA to assess the three-dimensional (3D) shapes of or to evaluate sex-related differences in the human brain, skull, rib cage, pelvis and lower limbs. Previous studies of the pediatric thoracic vertebrae suggest that they may undergo changes in shape as a result of normative growth. This study uses GPA and second order polynomial equations to model growth and age- and sex-related changes in shape of the pediatric thoracic spine. We present a thorough analysis of the normative 3D shape, size, and orientation of the pediatric thoracic spine and vertebrae as well as equations which can be used to generate models of the thoracic spine and vertebrae for any age between 1 and 19 years. Such models could be used to create more accurate 3D reconstructions of the thoracic spine, generate improved age-specific geometries for finite element models (FEMs) and used to assist clinicians with patient-specific planning and surgical interventions for spine deformity.

Original languageEnglish (US)
Pages (from-to)32-40
Number of pages9
JournalJournal of Biomechanics
Volume63
DOIs
StatePublished - Oct 3 2017
Externally publishedYes

Keywords

  • Generalized procrustes analysis
  • Growth
  • Model
  • Thoracic spine
  • Vertebrae

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

Fingerprint

Dive into the research topics of 'Characterization of the age-dependent shape of the pediatric thoracic spine and vertebrae using generalized procrustes analysis'. Together they form a unique fingerprint.

Cite this