Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis

J. Evans Patterson, B. L. Masecar, M. J. Zervos

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31 Scopus citations

Abstract

We identified two β-lactamase-positive enterococci. One strain was high-level (MIC, >2,000 μg/ml) gentamicin resistant; the other ws not (MIC, 12.5 μg/ml). β-Lactamase production was extrachromosomally mediated in both strains, and both strains showed an inoculum effect reversed by β-lactamase inhibitors. The strain lacking high-level gentamicin resistance showed synergistic killing with a combination of penicillin, clavulanic acid, and gentamicin.

Original languageEnglish (US)
Pages (from-to)122-124
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume32
Issue number1
StatePublished - Jan 1 1988

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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