Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis

Jan E Patterson, B. L. Masecar, M. J. Zervos

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

We identified two β-lactamase-positive enterococci. One strain was high-level (MIC, >2,000 μg/ml) gentamicin resistant; the other ws not (MIC, 12.5 μg/ml). β-Lactamase production was extrachromosomally mediated in both strains, and both strains showed an inoculum effect reversed by β-lactamase inhibitors. The strain lacking high-level gentamicin resistance showed synergistic killing with a combination of penicillin, clavulanic acid, and gentamicin.

Original languageEnglish (US)
Pages (from-to)122-124
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume32
Issue number1
StatePublished - 1988
Externally publishedYes

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Penicillinase
Enterococcus faecalis
Gentamicins
Clavulanic Acid
Enterococcus
Penicillins

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis. / Patterson, Jan E; Masecar, B. L.; Zervos, M. J.

In: Antimicrobial Agents and Chemotherapy, Vol. 32, No. 1, 1988, p. 122-124.

Research output: Contribution to journalArticle

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