TY - JOUR
T1 - Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis
AU - Evans Patterson, J.
AU - Masecar, B. L.
AU - Zervos, M. J.
PY - 1988
Y1 - 1988
N2 - We identified two β-lactamase-positive enterococci. One strain was high-level (MIC, >2,000 μg/ml) gentamicin resistant; the other ws not (MIC, 12.5 μg/ml). β-Lactamase production was extrachromosomally mediated in both strains, and both strains showed an inoculum effect reversed by β-lactamase inhibitors. The strain lacking high-level gentamicin resistance showed synergistic killing with a combination of penicillin, clavulanic acid, and gentamicin.
AB - We identified two β-lactamase-positive enterococci. One strain was high-level (MIC, >2,000 μg/ml) gentamicin resistant; the other ws not (MIC, 12.5 μg/ml). β-Lactamase production was extrachromosomally mediated in both strains, and both strains showed an inoculum effect reversed by β-lactamase inhibitors. The strain lacking high-level gentamicin resistance showed synergistic killing with a combination of penicillin, clavulanic acid, and gentamicin.
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U2 - 10.1128/aac.32.1.122
DO - 10.1128/aac.32.1.122
M3 - Article
C2 - 3126703
AN - SCOPUS:0023832816
VL - 32
SP - 122
EP - 124
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 1
ER -