Abstract
We identified two β-lactamase-positive enterococci. One strain was high-level (MIC, >2,000 μg/ml) gentamicin resistant; the other ws not (MIC, 12.5 μg/ml). β-Lactamase production was extrachromosomally mediated in both strains, and both strains showed an inoculum effect reversed by β-lactamase inhibitors. The strain lacking high-level gentamicin resistance showed synergistic killing with a combination of penicillin, clavulanic acid, and gentamicin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 122-124 |
| Number of pages | 3 |
| Journal | Antimicrobial agents and chemotherapy |
| Volume | 32 |
| Issue number | 1 |
| State | Published - Jan 1 1988 |
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ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases
Cite this
Evans Patterson, J., Masecar, B. L., & Zervos, M. J. (1988). Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis. Antimicrobial agents and chemotherapy, 32(1), 122-124.