Changes in the concentration of ions during senescence of the human erythrocyte.

Ivan L. Cameron; W. Elaine Hardman; Nancy K.R. Smith; Gary D. Fullerton; Attila Miseta

doi:10.1006/cbir.1993.1009

Changes in the concentration of ions during senescence of the human erythrocyte.

Ivan L. Cameron, W. Elaine Hardman, Nancy K.R. Smith, Gary D. Fullerton, Attila Miseta

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Flash frozen samples of normal human blood were cryosectioned and cryodried for electron probe x-ray microanalysis of the concentration of ions and elements in individual erythrocytes (RBCs). The data (expressed in mM/kg dry weight) demonstrated a systematic pattern of variation between the concentration of ions and elements in the RBCs. Specifically as K⁺ and Cl decreased in concentration, Ca²⁺ and sulfur increased in concentration. Phosphorous, Na⁺ and Mg²⁺ did not demonstrate a significant pattern of change. These findings are related to the dehydration and to the volume decrease that accompanies senescence of the RBC.

Original language	English (US)
Pages (from-to)	93-98
Number of pages	6
Journal	Cell Biology International
Volume	17
Issue number	1
DOIs	https://doi.org/10.1006/cbir.1993.1009
State	Published - Jan 1993
Externally published	Yes

ASJC Scopus subject areas

Cell Biology

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10.1006/cbir.1993.1009

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title = "Changes in the concentration of ions during senescence of the human erythrocyte.",

abstract = "Flash frozen samples of normal human blood were cryosectioned and cryodried for electron probe x-ray microanalysis of the concentration of ions and elements in individual erythrocytes (RBCs). The data (expressed in mM/kg dry weight) demonstrated a systematic pattern of variation between the concentration of ions and elements in the RBCs. Specifically as K+ and Cl decreased in concentration, Ca2+ and sulfur increased in concentration. Phosphorous, Na+ and Mg2+ did not demonstrate a significant pattern of change. These findings are related to the dehydration and to the volume decrease that accompanies senescence of the RBC.",

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AU - Smith, Nancy K.R.

AU - Fullerton, Gary D.

AU - Miseta, Attila

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Y1 - 1993/1

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AB - Flash frozen samples of normal human blood were cryosectioned and cryodried for electron probe x-ray microanalysis of the concentration of ions and elements in individual erythrocytes (RBCs). The data (expressed in mM/kg dry weight) demonstrated a systematic pattern of variation between the concentration of ions and elements in the RBCs. Specifically as K+ and Cl decreased in concentration, Ca2+ and sulfur increased in concentration. Phosphorous, Na+ and Mg2+ did not demonstrate a significant pattern of change. These findings are related to the dehydration and to the volume decrease that accompanies senescence of the RBC.

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Changes in the concentration of ions during senescence of the human erythrocyte.

Abstract

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