Changes in the concentration of ions during senescence of the human erythrocyte.

Ivan L. Cameron, W. Elaine Hardman, Nancy K.R. Smith, Gary D. Fullerton, Attila Miseta

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Flash frozen samples of normal human blood were cryosectioned and cryodried for electron probe x-ray microanalysis of the concentration of ions and elements in individual erythrocytes (RBCs). The data (expressed in mM/kg dry weight) demonstrated a systematic pattern of variation between the concentration of ions and elements in the RBCs. Specifically as K+ and Cl decreased in concentration, Ca2+ and sulfur increased in concentration. Phosphorous, Na+ and Mg2+ did not demonstrate a significant pattern of change. These findings are related to the dehydration and to the volume decrease that accompanies senescence of the RBC.

Original languageEnglish (US)
Pages (from-to)93-98
Number of pages6
JournalCell Biology International
Volume17
Issue number1
DOIs
StatePublished - Jan 1993
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology

Fingerprint

Dive into the research topics of 'Changes in the concentration of ions during senescence of the human erythrocyte.'. Together they form a unique fingerprint.

Cite this