Abstract
Changes in phagocytosis, chemotaxis, and nonspecific esterase staining of peritoneal exudate mononuclear cells occurred with aging in B6, AKR/J, and SJL/J mice. Different patterns of change with aging were observed with each of these three parameters in each of the strains. In the long-lived B6 mice, a progressive increase with aging in all three parameters was seen. In AKR/J mice, progressive increase in phagocytosis and nonspecific esterase staining was observed but a decline of chemotaxis occurred with aging. In SJL/J mice, all three parameters were very low early in life and each showed a significant increment upon reaching the age when the characteristic malignant lymphoreticular disease occurs.
Original language | English (US) |
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Pages (from-to) | 227-234 |
Number of pages | 8 |
Journal | Cellular Immunology |
Volume | 69 |
Issue number | 2 |
DOIs | |
State | Published - May 15 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology