Changes in electroshock convulsive response with repeated seizures

Marilyn Pollack, Fred Rosenthal, Robert Macey

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

This report describes the changes in the relationship between stimulus intensity and seizure duration with repeated shocking in rats during an experimental period of 47 days. The dependence of seizure duration on stimulus intensity diminishes with repeated shocking until finally all seizure durations become approximately equal. The decrease in duration of seizures after a relatively strong stimulating current occurs faster with more frequent shocking. The results are discussed in terms of two parameters, a, the decay constant of an excitatory state, and h/K, the minimal threshold for excitation.

Original languageEnglish (US)
Pages (from-to)98-106
Number of pages9
JournalExperimental Neurology
Volume7
Issue number2
DOIs
StatePublished - Feb 1963
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience

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