Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer

Ian M. Thompson, Joseph A. Basler, Robin Leach, Dean Troyer, Eric Klein, Otis Brawley

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Since 1991 and the activation of the Prostate Cancer Prevention Trial as well as similar prevention studies in several other organ sites, the interest in prostate cancer prevention has increased substantially. Despite such interest, the challenges to prevention trials-in design, implementation, prioritization, and allocation of resources-are substantial. Simultaneously, there has been an explosion in new targets and agents that may have an effect in the prevention of this disease. In this manuscript, we discuss these challenges to the study of prostate cancer prevention and provide a blueprint for prioritization of future studies.

Original languageEnglish (US)
Pages (from-to)73-78
Number of pages6
JournalUrologic Oncology: Seminars and Original Investigations
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Oncology
  • Urology

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