Cerebral hemodynamic response in Chinese (first) and English (second) language processing revealed by event-related functional MRI

Yonglin Pu, Ho Ling Liu, John A. Spinks, Srikanth Mahankali, Jinhu Xiong, Ching Mei Feng, Li Hai Tan, Peter T Fox, Jia Hong Gao

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Comparative functional neuroimaging studies using the block design paradigm have previously demonstrated that there are no significant differences in the location of areas of cerebral activation when native Chinese speakers independently process single words or sentences in both the Chinese (first) and English (second) languages. While it has also been documented that significant domains of brain response include the inferior to middle left frontal lobe, the latency, amplitude and duration of the associated hemodynamic changes during isolated neural processing of Chinese and English languages still remain unknown. The aim of this study, therefore, was to examine the characteristics of the hemodynamic alterations in the above-mentioned regions with event-related functional MRI (ER-fMRI) when native Chinese speakers performed verb generation tasks in both the Chinese (first) and English (second) languages. Our results demonstrate the presence of a similar neural activity-induced hemodynamic response in the inferior to middle left frontal lobe during both tasks. Further, there were also no statistically significant differences among the variables that described the hemodynamic response curves. These findings strongly imply that the underlying neural mechanism for Chinese (first) and English (second) language processing may be similar in native Chinese speakers.

Original languageEnglish (US)
Pages (from-to)643-647
Number of pages5
JournalMagnetic Resonance Imaging
Volume19
Issue number5
DOIs
StatePublished - 2001

Fingerprint

hemodynamic responses
Hemodynamics
Language
Magnetic Resonance Imaging
hemodynamics
Frontal Lobe
Processing
lobes
Functional neuroimaging
English language
Functional Neuroimaging
sentences
brain
Brain
Chemical activation
activation
curves

Keywords

  • Brain
  • Chinese Functional MRI
  • English
  • Event-related
  • Language

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Cerebral hemodynamic response in Chinese (first) and English (second) language processing revealed by event-related functional MRI. / Pu, Yonglin; Liu, Ho Ling; Spinks, John A.; Mahankali, Srikanth; Xiong, Jinhu; Feng, Ching Mei; Tan, Li Hai; Fox, Peter T; Gao, Jia Hong.

In: Magnetic Resonance Imaging, Vol. 19, No. 5, 2001, p. 643-647.

Research output: Contribution to journalArticle

Pu, Yonglin ; Liu, Ho Ling ; Spinks, John A. ; Mahankali, Srikanth ; Xiong, Jinhu ; Feng, Ching Mei ; Tan, Li Hai ; Fox, Peter T ; Gao, Jia Hong. / Cerebral hemodynamic response in Chinese (first) and English (second) language processing revealed by event-related functional MRI. In: Magnetic Resonance Imaging. 2001 ; Vol. 19, No. 5. pp. 643-647.
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