Cellular Senescence: Defining a Path Forward

Vassilis Gorgoulis; Peter D. Adams; Andrea Alimonti; Dorothy C. Bennett; Oliver Bischof; Cleo Bishop; Judith Campisi; Manuel Collado; Konstantinos Evangelou; Gerardo Ferbeyre; Jesús Gil; Eiji Hara; Valery Krizhanovsky; Diana Jurk; Andrea B. Maier; Masashi Narita; Laura Niedernhofer; João F. Passos; Paul D. Robbins; Clemens A. Schmitt; John Sedivy; Konstantinos Vougas; Thomas von Zglinicki; Daohong Zhou; Manuel Serrano; Marco Demaria

doi:10.1016/j.cell.2019.10.005

Cellular Senescence: Defining a Path Forward

Vassilis Gorgoulis
, Peter D. Adams
, Andrea Alimonti
, Dorothy C. Bennett
, Oliver Bischof
, Cleo Bishop
, Judith Campisi
, Manuel Collado
, Konstantinos Evangelou
, Gerardo Ferbeyre
, Jesús Gil
, Eiji Hara
, Valery Krizhanovsky
, Diana Jurk
, Andrea B. Maier
, Masashi Narita
, Laura Niedernhofer
, João F. Passos
, Paul D. Robbins
, Clemens A. Schmitt

John Sedivy, Konstantinos Vougas, Thomas von Zglinicki, Daohong Zhou, Manuel Serrano, Marco Demaria

Research output: Contribution to journal › Review article › peer-review

2365 Scopus citations

Abstract

The cellular state of “senescence” has proven difficult to define, presenting an obstacle for progress in the field. This perspective provides a consensus on the cellular and molecular features of senescence from 26 field leaders.

Original language	English (US)
Pages (from-to)	813-827
Number of pages	15
Journal	Cell
Volume	179
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2019.10.005
State	Published - Oct 31 2019
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2019.10.005

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Gorgoulis, V., Adams, P. D., Alimonti, A., Bennett, D. C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., Gil, J., Hara, E., Krizhanovsky, V., Jurk, D., Maier, A. B., Narita, M., Niedernhofer, L., Passos, J. F., Robbins, P. D., ... Demaria, M. (2019). Cellular Senescence: Defining a Path Forward. Cell, 179(4), 813-827. https://doi.org/10.1016/j.cell.2019.10.005

Gorgoulis, V, Adams, PD, Alimonti, A, Bennett, DC, Bischof, O, Bishop, C, Campisi, J, Collado, M, Evangelou, K, Ferbeyre, G, Gil, J, Hara, E, Krizhanovsky, V, Jurk, D, Maier, AB, Narita, M, Niedernhofer, L, Passos, JF, Robbins, PD, Schmitt, CA, Sedivy, J, Vougas, K, von Zglinicki, T, Zhou, D, Serrano, M & Demaria, M 2019, 'Cellular Senescence: Defining a Path Forward', Cell, vol. 179, no. 4, pp. 813-827. https://doi.org/10.1016/j.cell.2019.10.005

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title = "Cellular Senescence: Defining a Path Forward",

abstract = "The cellular state of “senescence” has proven difficult to define, presenting an obstacle for progress in the field. This perspective provides a consensus on the cellular and molecular features of senescence from 26 field leaders.",

author = "Vassilis Gorgoulis and Adams, \{Peter D.\} and Andrea Alimonti and Bennett, \{Dorothy C.\} and Oliver Bischof and Cleo Bishop and Judith Campisi and Manuel Collado and Konstantinos Evangelou and Gerardo Ferbeyre and Jes{\'u}s Gil and Eiji Hara and Valery Krizhanovsky and Diana Jurk and Maier, \{Andrea B.\} and Masashi Narita and Laura Niedernhofer and Passos, \{Jo{\~a}o F.\} and Robbins, \{Paul D.\} and Schmitt, \{Clemens A.\} and John Sedivy and Konstantinos Vougas and \{von Zglinicki\}, Thomas and Daohong Zhou and Manuel Serrano and Marco Demaria",

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AU - Gorgoulis, Vassilis

AU - Adams, Peter D.

AU - Alimonti, Andrea

AU - Bennett, Dorothy C.

AU - Bischof, Oliver

AU - Bishop, Cleo

AU - Campisi, Judith

AU - Collado, Manuel

AU - Evangelou, Konstantinos

AU - Ferbeyre, Gerardo

AU - Gil, Jesús

AU - Hara, Eiji

AU - Krizhanovsky, Valery

AU - Jurk, Diana

AU - Maier, Andrea B.

AU - Narita, Masashi

AU - Niedernhofer, Laura

AU - Passos, João F.

AU - Robbins, Paul D.

AU - Schmitt, Clemens A.

AU - Sedivy, John

AU - Vougas, Konstantinos

AU - von Zglinicki, Thomas

AU - Zhou, Daohong

AU - Serrano, Manuel

AU - Demaria, Marco

PY - 2019/10/31

Y1 - 2019/10/31

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AB - The cellular state of “senescence” has proven difficult to define, presenting an obstacle for progress in the field. This perspective provides a consensus on the cellular and molecular features of senescence from 26 field leaders.

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DO - 10.1016/j.cell.2019.10.005

M3 - Review article

C2 - 31675495

AN - SCOPUS:85074054595

SN - 0092-8674

VL - 179

SP - 813

EP - 827

JO - Cell

JF - Cell

IS - 4

ER -

Cellular Senescence: Defining a Path Forward

Abstract

ASJC Scopus subject areas

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