Causes of TIPS dysfunction

Marco Cura, Alejandro Cura, Rajeev Suri, Fadi El-Merhi, Jorge Lopera, Ghazwan Kroma

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations


OBJECTIVE. Transjugular intrahepatic portosystemic shunt (TIPS) creation is an effective method to control portal hypertension. TIPS creations with bare stents have shown limited and unpredictable patency. In nearly all cases of rebleeding or recurrent ascites after TIPS creation, there is shunt stenosis or occlusion. The purpose of this article is to review the biologic and technical factors that predispose to TIPS failure and how the use of an expandable polytetrafluoroethylene (PTFE)-covered-stent has significantly improved TIPS patency. CONCLUSION. Biologic and technical factors may predispose to shunt failure. The combination of improved technique and expandable PTFE has significantly improved TIPS patency. The need for follow-up venography and secondary interventions has been reduced significantly as a result of improved shunt patency.

Original languageEnglish (US)
Pages (from-to)1751-1757
Number of pages7
JournalAmerican Journal of Roentgenology
Issue number6
StatePublished - Dec 2008


  • Covered stent
  • Interventional radiology
  • Portal hypertension
  • Transjugular intrahepatic portosystemic shunt

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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