Caspofungin in combination with amphotericin B against Candida glabrata

Francesco Barchiesi, Elisabetta Spreghini, Annette W. Fothergill, Daniela Arzeni, Gianfranco Greganti, Daniele Giannini, Michael G. Rinaldi, Giorgio Scalise

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

The effects of caspofungin combined with amphotericin B were investigated with Candida glabrata. Although in vitro experiments showed an indifferent interaction, the combination regimen was the only therapeutic approach yielding organ sterilization in a murine candidemia model.

Original languageEnglish (US)
Pages (from-to)2546-2549
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume49
Issue number6
DOIs
StatePublished - Jun 1 2005

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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  • Cite this

    Barchiesi, F., Spreghini, E., Fothergill, A. W., Arzeni, D., Greganti, G., Giannini, D., Rinaldi, M. G., & Scalise, G. (2005). Caspofungin in combination with amphotericin B against Candida glabrata. Antimicrobial agents and chemotherapy, 49(6), 2546-2549. https://doi.org/10.1128/AAC.49.6.2546-2549.2005