Case report of visual biofeedback-driven, magnetic resonance-guided single-fraction SABR in breath hold for early stage non–small-cell lung cancer

Michael D. Chuong, Rupesh Kotecha, Minesh P. Mehta, Sonia Adamson, Tino Romaguera, Matthew D. Hall, Diane Alvarez, Alonso N. Gutierrez, Vivek Mishra, Fernando De Zarraga, Kathryn E. Mittauer

Research output: Contribution to journalArticlepeer-review

Abstract

Stereotactic ablative body radiation therapy (SABR) is a well-established alternative to surgery for early stage non–small-cell lung cancer (NSCLC). While SABR is typically delivered in 3 to 5 fractions, randomized trials have shown single-fraction SABR to be a reasonable alternative. We present the case of a 66-year-old male with history of cholangiocarcinoma who was subsequently diagnosed with peripheral early stage NSCLC and treated in mid-inspiration breath hold (BH) to 34 Gy in 1 fraction on a magnetic resonance (MR)-guided linear accelerator, with treatment delivery completed in 17 minutes. Visual biofeedback was utilized to maximize patient compliance with appropriate depth of inspiration BH and improve overall treatment delivery time efficiency. The benefits of single- vs multifraction SABR and unique advantages of MR guidance that are particularly well-suited for single-fraction SABR are reviewed.

Original languageEnglish (US)
Pages (from-to)247-252
Number of pages6
JournalMedical Dosimetry
Volume46
Issue number3
DOIs
StatePublished - Sep 1 2021
Externally publishedYes

Keywords

  • Lung cancer
  • MR-guided radiation therapy
  • SABR, SBRT
  • Single fraction

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Oncology
  • Radiology Nuclear Medicine and imaging

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