Case report: Fulminant murine typhus presenting with status epilepticus and multi-organ failure: An autopsy case and a review of the neurologic presentations of murine typhus

Benjamin E. Stephens, Meilinh Thi, Rahaf Alkhateb, Apeksha Agarwal, Francis E. Sharkey, Christopher Dayton, Gregory M. Anstead

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Murine typhus (MT) is an important cause of febrile illness in endemic areas, and there is an epidemiologic resurgence of this infection currently transpiring in Texas and California. Fatal cases and severe neurological complications are rare. A fatal case of MT in a middle-aged man is reported with a course culminating in multi-organ failure and refractory status epilepticus. An autopsy revealed hemorrhagic pneumonia, acute tubular necrosis, and ischemic necrosis in the liver, adrenals, and brain. We have also reviewed the neurologic complications of MT.

Original languageEnglish (US)
Pages (from-to)306-309
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume99
Issue number2
DOIs
StatePublished - Jan 1 2018

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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