TY - JOUR
T1 - Case report
T2 - Fulminant murine typhus presenting with status epilepticus and multi-organ failure: An autopsy case and a review of the neurologic presentations of murine typhus
AU - Stephens, Benjamin E.
AU - Thi, Meilinh
AU - Alkhateb, Rahaf
AU - Agarwal, Apeksha
AU - Sharkey, Francis E.
AU - Dayton, Christopher
AU - Anstead, Gregory M.
N1 - Publisher Copyright:
Copyright © 2018 by The American Society of Tropical Medicine and Hygiene.
PY - 2018
Y1 - 2018
N2 - Murine typhus (MT) is an important cause of febrile illness in endemic areas, and there is an epidemiologic resurgence of this infection currently transpiring in Texas and California. Fatal cases and severe neurological complications are rare. A fatal case of MT in a middle-aged man is reported with a course culminating in multi-organ failure and refractory status epilepticus. An autopsy revealed hemorrhagic pneumonia, acute tubular necrosis, and ischemic necrosis in the liver, adrenals, and brain. We have also reviewed the neurologic complications of MT.
AB - Murine typhus (MT) is an important cause of febrile illness in endemic areas, and there is an epidemiologic resurgence of this infection currently transpiring in Texas and California. Fatal cases and severe neurological complications are rare. A fatal case of MT in a middle-aged man is reported with a course culminating in multi-organ failure and refractory status epilepticus. An autopsy revealed hemorrhagic pneumonia, acute tubular necrosis, and ischemic necrosis in the liver, adrenals, and brain. We have also reviewed the neurologic complications of MT.
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U2 - 10.4269/ajtmh.18-0084
DO - 10.4269/ajtmh.18-0084
M3 - Article
C2 - 29943716
AN - SCOPUS:85051056216
SN - 0002-9637
VL - 99
SP - 306
EP - 309
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 2
ER -