Cardiovascular Risk Assessment Varies Widely by Calculator and Race/Ethnicity in a Majority Latinx Cohort Living with HIV

Yuanyuan Liang, Norma S. Ketchum, Barbara Turner, John Flores, Delia Bullock, Roberto Villarreal, Polly H. Noël, Michael T. Yin, Barbara S. Taylor

Research output: Contribution to journalArticle

Abstract

Comparison of cardiovascular disease (CVD) risk calculators in Latinx majority populations living with HIV can assist clinicians in selecting a calculator and interpreting results. 10-year CVD risks were estimated for 652 patients seen ≥ 2 times over 12 months in a public clinic using three risk calculators: Atherosclerotic CVD risk Calculator (ASCVD), Framingham Risk Calculator (FRC), and Data Collection on Adverse Effects of Anti-HIV Drugs Study (D:A:D) Calculator. Median estimated 10-year CVD risk in this population was highest using FRC (11%), followed by D:A:D (10%), and lowest with ASCVD (5%; p < 0.001). However, D:A:D classified 44.3% in a high/very high risk category compared to FRC (20.7%) and ASCVD (33.4%) (all p < 0.001). ASCVD risk estimates differed significantly by race/ethnicity (p < 0.001). Risk varied widely across three risk calculators and by race/ethnicity, and providers should be aware of these differences when choosing a calculator for use in majority minority populations.

Original languageEnglish (US)
Pages (from-to)323-335
Number of pages13
JournalJournal of Immigrant and Minority Health
Volume22
Issue number2
DOIs
StatePublished - Apr 1 2020

Keywords

  • Cardiovascular risk
  • Cardiovascular risk calculation
  • Ethnicity
  • HIV
  • Hispanic
  • Race

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health

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