Cardiovascular Risk Assessment Varies Widely by Calculator and Race/Ethnicity in a Majority Latinx Cohort Living with HIV

Yuanyuan Liang, Norma S. Ketchum, Barbara J. Turner, John Flores, Delia Bullock, Roberto Villarreal, Polly H. Noël, Michael T. Yin, Barbara S. Taylor

Research output: Contribution to journalArticle


Comparison of cardiovascular disease (CVD) risk calculators in Latinx majority populations living with HIV can assist clinicians in selecting a calculator and interpreting results. 10-year CVD risks were estimated for 652 patients seen ≥ 2 times over 12 months in a public clinic using three risk calculators: Atherosclerotic CVD risk Calculator (ASCVD), Framingham Risk Calculator (FRC), and Data Collection on Adverse Effects of Anti-HIV Drugs Study (D:A:D) Calculator. Median estimated 10-year CVD risk in this population was highest using FRC (11%), followed by D:A:D (10%), and lowest with ASCVD (5%; p < 0.001). However, D:A:D classified 44.3% in a high/very high risk category compared to FRC (20.7%) and ASCVD (33.4%) (all p < 0.001). ASCVD risk estimates differed significantly by race/ethnicity (p < 0.001). Risk varied widely across three risk calculators and by race/ethnicity, and providers should be aware of these differences when choosing a calculator for use in majority minority populations.

Original languageEnglish (US)
Pages (from-to)323-335
Number of pages13
JournalJournal of Immigrant and Minority Health
Issue number2
StatePublished - Apr 1 2020



  • Cardiovascular risk
  • Cardiovascular risk calculation
  • Ethnicity
  • HIV
  • Hispanic
  • Race

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health

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