Cardiovascular responses to environmental heating in unanesthetized baboons

D. W. Proppe, G. L. Brengelmann, T. C. Ruch

Research output: Contribution to journalArticlepeer-review

Abstract

Experiments were performed on unanesthetized chaired baboons to assess their cardiovascular responses during a 1 to 2 hr. exposure to high ambient temperatures (40 to 45°C). Recorded variables were internal temperature (T(c)), skin temperature (T(s)) at several sites, left renal artery blood flow, terminal aorta or right common iliac artery blood flow, aortic blood pressure, and heart rate. Responses observed in all heating experiments are a rapid followed by a slow rise in T(s); a progressive increase in T(c) to 1.5 to 3.0°C above control level; a progressive increase in iliac/terminal aorta flow from 200 to 400% above control level; a progressive decline in mean aortic pressure which reached a nadir at 75 to 90% of control level within 45 min. after commencement of heating and then was either maintained at the low level or began to increase again; and an increase in heart rate from 40 to 90% above control levels. The renal blood flow during heating responded differently among the animals; at one extreme, some animals had a 40 to 60% decline in renal flow, whereas others had only a slight decline in renal flow. Therefore, some animals partially meet the need for increased leg flow (presumably to the skin) by reducing blood flow to the kidney as well as by a probable increase in cardiac output.

Original languageEnglish (US)
Pages (from-to)1054
Number of pages1
JournalFederation Proceedings
Volume32
Issue number3 I
StatePublished - 1973
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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