Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders

Jaewon Yoon, Tom W. Eyster, Asish C. Misra, Joerg Lahann

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardiomyocyte contraction. These microcylinders can find applications in a host of micromechanical systems.

Original languageEnglish (US)
Pages (from-to)4509-4515
Number of pages7
JournalAdvanced Materials
Volume27
Issue number30
DOIs
StatePublished - Aug 1 2015
Externally publishedYes

Keywords

  • bioactuators
  • biodegradable polymers
  • electrohydrodynamic cojetting
  • microparticles
  • surface chemistry

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering

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