Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders

Jaewon Yoon; Tom W. Eyster; Asish C. Misra; Joerg Lahann

doi:10.1002/adma.201501284

Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders

Jaewon Yoon, Tom W. Eyster, Asish C. Misra, Joerg Lahann

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardiomyocyte contraction. These microcylinders can find applications in a host of micromechanical systems.

Original language	English (US)
Pages (from-to)	4509-4515
Number of pages	7
Journal	Advanced Materials
Volume	27
Issue number	30
DOIs	https://doi.org/10.1002/adma.201501284
State	Published - Aug 1 2015
Externally published	Yes

Keywords

bioactuators
biodegradable polymers
electrohydrodynamic cojetting
microparticles
surface chemistry

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201501284

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title = "Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders",

abstract = "Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardiomyocyte contraction. These microcylinders can find applications in a host of micromechanical systems.",

keywords = "bioactuators, biodegradable polymers, electrohydrodynamic cojetting, microparticles, surface chemistry",

author = "Jaewon Yoon and Eyster, {Tom W.} and Misra, {Asish C.} and Joerg Lahann",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.",

year = "2015",

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doi = "10.1002/adma.201501284",

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AU - Yoon, Jaewon

AU - Eyster, Tom W.

AU - Misra, Asish C.

AU - Lahann, Joerg

PY - 2015/8/1

Y1 - 2015/8/1

N2 - Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardiomyocyte contraction. These microcylinders can find applications in a host of micromechanical systems.

AB - Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardiomyocyte contraction. These microcylinders can find applications in a host of micromechanical systems.

KW - bioactuators

KW - biodegradable polymers

KW - electrohydrodynamic cojetting

KW - microparticles

KW - surface chemistry

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ER -

Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders

Abstract

Keywords

ASJC Scopus subject areas

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