TY - JOUR
T1 - Cardiac complications of COVID-19
T2 - Incidence and outcomes
AU - Pillarisetti, Jayasree
AU - Cheema, Mubeen S.
AU - Haloot, Justin
AU - Panday, Manoj
AU - Badin, Auroa
AU - Mehta, Anjlee
AU - Anderson, Allen S.
AU - Prasad, Anand
N1 - Publisher Copyright:
© 2022 Cardiological Society of India
PY - 2022/5/1
Y1 - 2022/5/1
N2 - Background: Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown. Objectives: We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19. Methods: Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data. Results: The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7–7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality. Conclusions: Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.
AB - Background: Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown. Objectives: We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19. Methods: Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data. Results: The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7–7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality. Conclusions: Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.
KW - COVID-19
KW - Cardiac complications
KW - Mortality
KW - SARS-CoV-2
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U2 - 10.1016/j.ihj.2022.04.008
DO - 10.1016/j.ihj.2022.04.008
M3 - Article
C2 - 35490848
AN - SCOPUS:85130032429
SN - 0019-4832
VL - 74
SP - 170
EP - 177
JO - Indian Heart Journal
JF - Indian Heart Journal
IS - 3
ER -