Carbapenem-Resistant Enterobacterales Infection after Massive Blast Injury: Use of Cefiderocol Based Combination Therapy

B. W. Carney; J. A. Rizzo; J. F. Alderete; R. Cindass; A. E. Markelz; L. C. Cancio

doi:10.1093/milmed/usab350

Carbapenem-Resistant Enterobacterales Infection after Massive Blast Injury: Use of Cefiderocol Based Combination Therapy

B. W. Carney
, J. A. Rizzo
, J. F. Alderete
, R. Cindass
, A. E. Markelz
, L. C. Cancio

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A military soldier sustained a blast injury in Afghanistan, resulting in amputations and hemipelvectomy. He developed New Delhi metallo-beta-lactamase-producing E. coli bacteremia, soft-tissue infection, and sacral osteomyelitis. These organisms are being increasingly discovered in different communities around the world. He was successfully treated with tigecycline and cefiderocol. Cefiderocol is a novel siderophore-based cephalosporine developed to treat serious infections, including those caused by carbapenem-resistant Enterobacterales.

Original language	English (US)
Pages (from-to)	1241-1245
Number of pages	5
Journal	Military medicine
Volume	186
Issue number	11-12
DOIs	https://doi.org/10.1093/milmed/usab350
State	Published - Nov 1 2021
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Access to Document

10.1093/milmed/usab350

Cite this

@article{621f301ba8174e06a5cf5762464c501c,

title = "Carbapenem-Resistant Enterobacterales Infection after Massive Blast Injury: Use of Cefiderocol Based Combination Therapy",

abstract = "A military soldier sustained a blast injury in Afghanistan, resulting in amputations and hemipelvectomy. He developed New Delhi metallo-beta-lactamase-producing E. coli bacteremia, soft-tissue infection, and sacral osteomyelitis. These organisms are being increasingly discovered in different communities around the world. He was successfully treated with tigecycline and cefiderocol. Cefiderocol is a novel siderophore-based cephalosporine developed to treat serious infections, including those caused by carbapenem-resistant Enterobacterales.",

author = "Carney, \{B. W.\} and Rizzo, \{J. A.\} and Alderete, \{J. F.\} and R. Cindass and Markelz, \{A. E.\} and Cancio, \{L. C.\}",

note = "Publisher Copyright: {\textcopyright} 2021.",

year = "2021",

month = nov,

day = "1",

doi = "10.1093/milmed/usab350",

language = "English (US)",

volume = "186",

pages = "1241--1245",

journal = "Military medicine",

issn = "0026-4075",

publisher = "Oxford University Press",

number = "11-12",

}

TY - JOUR

T1 - Carbapenem-Resistant Enterobacterales Infection after Massive Blast Injury

T2 - Use of Cefiderocol Based Combination Therapy

AU - Carney, B. W.

AU - Rizzo, J. A.

AU - Alderete, J. F.

AU - Cindass, R.

AU - Markelz, A. E.

AU - Cancio, L. C.

PY - 2021/11/1

Y1 - 2021/11/1

N2 - A military soldier sustained a blast injury in Afghanistan, resulting in amputations and hemipelvectomy. He developed New Delhi metallo-beta-lactamase-producing E. coli bacteremia, soft-tissue infection, and sacral osteomyelitis. These organisms are being increasingly discovered in different communities around the world. He was successfully treated with tigecycline and cefiderocol. Cefiderocol is a novel siderophore-based cephalosporine developed to treat serious infections, including those caused by carbapenem-resistant Enterobacterales.

AB - A military soldier sustained a blast injury in Afghanistan, resulting in amputations and hemipelvectomy. He developed New Delhi metallo-beta-lactamase-producing E. coli bacteremia, soft-tissue infection, and sacral osteomyelitis. These organisms are being increasingly discovered in different communities around the world. He was successfully treated with tigecycline and cefiderocol. Cefiderocol is a novel siderophore-based cephalosporine developed to treat serious infections, including those caused by carbapenem-resistant Enterobacterales.

UR - https://www.scopus.com/pages/publications/85119531780

UR - https://www.scopus.com/pages/publications/85119531780#tab=citedBy

U2 - 10.1093/milmed/usab350

DO - 10.1093/milmed/usab350

M3 - Article

C2 - 34453163

AN - SCOPUS:85119531780

SN - 0026-4075

VL - 186

SP - 1241

EP - 1245

JO - Military medicine

JF - Military medicine

IS - 11-12

ER -

Carbapenem-Resistant Enterobacterales Infection after Massive Blast Injury: Use of Cefiderocol Based Combination Therapy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this