Abstract
Candida albicans meningitis was diagnosed in a 45-day-old premature infant whose birth weight was 1,616 gm. Symptoms consisted of poor weight gain and poor sucking. The combined use of amphotericin B and 5-fluorocytosine (5-FC) resulted in negative CSF cultures after 12 days of therapy. Amphotericin B was given for 45 days (total 83 mg) and 5-FC for 60 days (total 19 mg). Only one other premature infant has been reported in the literature who had similar treatment. A review of Candida meningitis diagnosed before death in 11 other infants less than 1 year of age is presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 57-61 |
| Number of pages | 5 |
| Journal | Pediatrics |
| Volume | 61 |
| Issue number | 1 |
| State | Published - 1978 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Candida albicans meningitis in a premature neonate successfully treated with 5-fluorocytosine and amphotericin B : A case report and review of the literature. / Lilien, L. D.; Ramamurthy, R. S.; Pildes, R. S.
In: Pediatrics, Vol. 61, No. 1, 1978, p. 57-61.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Candida albicans meningitis in a premature neonate successfully treated with 5-fluorocytosine and amphotericin B
T2 - A case report and review of the literature
AU - Lilien, L. D.
AU - Ramamurthy, R. S.
AU - Pildes, R. S.
PY - 1978
Y1 - 1978
N2 - Candida albicans meningitis was diagnosed in a 45-day-old premature infant whose birth weight was 1,616 gm. Symptoms consisted of poor weight gain and poor sucking. The combined use of amphotericin B and 5-fluorocytosine (5-FC) resulted in negative CSF cultures after 12 days of therapy. Amphotericin B was given for 45 days (total 83 mg) and 5-FC for 60 days (total 19 mg). Only one other premature infant has been reported in the literature who had similar treatment. A review of Candida meningitis diagnosed before death in 11 other infants less than 1 year of age is presented.
AB - Candida albicans meningitis was diagnosed in a 45-day-old premature infant whose birth weight was 1,616 gm. Symptoms consisted of poor weight gain and poor sucking. The combined use of amphotericin B and 5-fluorocytosine (5-FC) resulted in negative CSF cultures after 12 days of therapy. Amphotericin B was given for 45 days (total 83 mg) and 5-FC for 60 days (total 19 mg). Only one other premature infant has been reported in the literature who had similar treatment. A review of Candida meningitis diagnosed before death in 11 other infants less than 1 year of age is presented.
UR - http://www.scopus.com/inward/record.url?scp=0017843288&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017843288&partnerID=8YFLogxK
M3 - Article
C2 - 263875
AN - SCOPUS:0017843288
VL - 61
SP - 57
EP - 61
JO - Pediatrics
JF - Pediatrics
SN - 0031-4005
IS - 1
ER -