Cancer omics: From regulatory networks to clinical outcomes

Binhua Tang, Pei Yin Hsu, Tim H.M. Huang, Victor X. Jin

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Current limitation in cancer genomic studies is a lack of the integration of various omics data generated through next generation sequencing technologies, as well as a lack of the sounding and comprehensive epigenomic and genomic information about a particular cancer cell type. In this review, we will discuss main aspects of current genomics research with its application in cancer topics. We will first overview the next-generation sequencing technologies, then outline the major computational approaches, particularly focusing on ChIP-based omics data, and list several remaining open questions facing computational biologists, further present regulatory network analysis inferred from the ChIP-based omics data; finally implicate the clinical outcomes from the network and pathway analysis.

Original languageEnglish (US)
Pages (from-to)277-283
Number of pages7
JournalCancer Letters
Issue number2
StatePublished - Nov 1 2013


  • Cancer omics
  • Clinical outcomes
  • Next generation sequencing
  • Regulatory networks

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


Dive into the research topics of 'Cancer omics: From regulatory networks to clinical outcomes'. Together they form a unique fingerprint.

Cite this