Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository

Lisa F. Newcomb, James D. Brooks, Peter R. Carroll, Ziding Feng, Martin E. Gleave, Peter S. Nelson, Ian M. Thompson, Daniel W. Lin

Research output: Contribution to journalReview article

49 Scopus citations

Abstract

Active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance from the indolent cancers. The Canary Prostate Active Surveillance Study is a multicenter study and a biorepository that will discover and confirm biomarkers of aggressive disease as defined by histologic, prostate-specific antigen, or clinical criteria.

Original languageEnglish (US)
Pages (from-to)407-413
Number of pages7
JournalUrology
Volume75
Issue number2
DOIs
StatePublished - Feb 2010

ASJC Scopus subject areas

  • Urology

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    Newcomb, L. F., Brooks, J. D., Carroll, P. R., Feng, Z., Gleave, M. E., Nelson, P. S., Thompson, I. M., & Lin, D. W. (2010). Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository. Urology, 75(2), 407-413. https://doi.org/10.1016/j.urology.2009.05.050